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In 1650, while Robert, a young medical student, steels himself to assist with her dissection, twenty-two-year-old housemaid Anne Green recalls her life as she lies in her coffin, presumed dead after being hanged for murdering her child that was, in fact, stillborn.

In 1645 in England, the daughters of the town minister successfully accuse a local healer and her granddaughter of witchcraft to conceal an out-of-wedlock pregnancy, but years later during the 1692 Salem trials their lie has unexpected repercussions.